WE ARE RARE

Fulcrum is a great place to have a career. Why? Because we have the FULcrew! Our people make us great. At Fulcrum, you can count on finding coworkers who are passionate about their work. Our patient-centered, inclusive, and connected culture enables us to actively listen to the needs of the rare disease community as we lead our science. This makes us and our work rare!

View our open roles

OUR VALUES:

Passionate.

We show up every day with commitment, purpose, and dedication to patients, the business, and each other.

Transformative.

We are scientific leaders focused on creating therapies that transform the lives of patients and caregivers.

Inclusive.

We are committed to a diverse, welcoming, and unique culture that embraces and celebrates everyone. We strive to be as diverse as the community we serve.

Patient-Centered.

We actively listen to the needs of patients, caregivers, and our community as we lead our science. Patients and the advocacy community are the foundation of everything we do.

Connected.

We invest in our people so we can learn, innovate, and grow together. Empowerment and camaraderie are pivotal to our progress.

Make your career a career with impact.

See our available roles below or connect with us at [email protected]

Join the FULcrew

Voices of Fulcrum

Meet the FULcrew and hear our stories.

Are you looking for consistency, commitment, and passion in your career? Join us.

There is always hope for change when people are committed to moving forward together every day, without exception. We call this steadfast commitment our "20 Mile March," inspired by Jim Collins' book Good to Great. At Fulcrum, we pledge to show up passionately every day, dedicated to our work and each other, no matter the challenges we face.

Explore our job openings:

Brian joined Fulcrum at a pivotal time. Discover what stood out to him about the FULcrew and why it made all the difference!

#MomentsThatMatter #FULcrew

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Brian joined Fulcrum at a pivotal time. Discover what stood out to him about the FULcrew and why it made all the difference! #MomentsThatMatter #FULcrew

Danielle Branch had the honor of speaking at the Sickle Cell Advocates of Rochester Virtual Educational Session this month.

Attendees in person were encouraged to “Write Their Own Story” through the arts–whether singing, dancing, writing, painting, or poetry.

Thank you, Sickle Cell Advocates of Rochester, for having us and for empowering voices in the Sickle Cell Community!

#SickleCellAwareness #WriteYourOwnStory

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Danielle Branch had the honor of speaking at the Sickle Cell Advocates of Rochester Virtual Educational Session this month. Attendees in person were encouraged to “Write Their Own Story” through the arts–whether singing, dancing, writing, painting, or poetry. Thank you, Sickle Cell Advocates of Rochester, for having us and for empowering voices in the Sickle Cell Community! #SickleCellAwareness #WriteYourOwnStory

As a key member of Fulcrum’s People Experience Team, Pam’s favorite core value is "Connected." Watch this quick video to hear why this value resonates with her the most.

#ConnectedAtFulcrum

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As a key member of Fulcrum’s People Experience Team, Pam’s favorite core value is "Connected." Watch this quick video to hear why this value resonates with her the most. #ConnectedAtFulcrum

Fulcrum was thrilled to be a part of Saturday’s `Building Bridges: Connecting Communities for Sickle Cell Awareness` in Gulfport, MS. Hosted by the @mssicklecellfoundation and the @morgan.legacy.group, it was a powerful day of learning, community, action and raising awareness for Sickle Cell Warriors.

Pictured (L to R): Danielle Branch, Fulcrum Therapeutics and Natasha Roberts, Vice Chairwoman Mississippi Sickle Cell Foundation

#scdawareness #sicklecelldisease

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Fulcrum was thrilled to be a part of Saturday’s 'Building Bridges: Connecting Communities for Sickle Cell Awareness' in Gulfport, MS. Hosted by the @mssicklecellfoundation and the @morgan.legacy.group, it was a powerful day of learning, community, action and raising awareness for Sickle Cell Warriors. Pictured (L to R): Danielle Branch, Fulcrum Therapeutics and Natasha Roberts, Vice Chairwoman Mississippi Sickle Cell Foundation #scdawareness #sicklecelldisease

We were honored to participate in the @cayennewellness 16th Annual Sickle Cell Disease Educational Summit in California this week. Over four days, the summit comprehensively addressed various aspects of sickle cell disease, trait awareness, and education. It’s always an inspiration to spend time with the SCD Community, especially during Sickle Cell Awareness Month.

Pictured: Mel Hayes, Danielle Branch

#SCDAwarenessMonth #CayenneWellnessSummit #SickleCellAwareness

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We were honored to participate in the @cayennewellness 16th Annual Sickle Cell Disease Educational Summit in California this week. Over four days, the summit comprehensively addressed various aspects of sickle cell disease, trait awareness, and education. It’s always an inspiration to spend time with the SCD Community, especially during Sickle Cell Awareness Month. Pictured: Mel Hayes, Danielle Branch #SCDAwarenessMonth #CayenneWellnessSummit #SickleCellAwareness

At Fulcrum, we are dedicated to transforming the lives of people with Sickle Cell Disease every day, but September gives us a special opportunity to spotlight the SCD community.

During Sickle Cell Awareness Month, we highlight the daily challenges and inspiring strength of SCD warriors. SCD is an area of high unmet need, and we are honored to support the community through our research, advocacy, and partnership.

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At Fulcrum, we are dedicated to transforming the lives of people with Sickle Cell Disease every day, but September gives us a special opportunity to spotlight the SCD community. During Sickle Cell Awareness Month, we highlight the daily challenges and inspiring strength of SCD warriors. SCD is an area of high unmet need, and we are honored to support the community through our research, advocacy, and partnership.

Topline data results from the Phase 3 REACH trial of losmapimod for patients living with Facioscapulohumeral Muscular Dystrophy (FSHD) did not achieve its primary endpoint of change from baseline in reachable workspace.

Read the full press release here: https://ir.fulcrumtx.com/news-releases/news-release-details/fulcrum-therapeutics-announces-topline-results-phase-3-reach

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Topline data results from the Phase 3 REACH trial of losmapimod for patients living with Facioscapulohumeral Muscular Dystrophy (FSHD) did not achieve its primary endpoint of change from baseline in reachable workspace. Read the full press release here: https://ir.fulcrumtx.com/news-releases/news-release-details/fulcrum-therapeutics-announces-topline-results-phase-3-reach
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